Human XL Cytokine Discovery Luminex® High Performance Assay

Human XL Cytokine Discovery Luminex

Why Choose the Human XL Cytokine Discovery Panel?

  • Broad selection – choose any combination from all 45 analytes
  • Superior accuracy – tested side-by-side with other leading suppliers
  • Flexible – order any combination of analytes within the panel
  • Easy to order – select analytes directly from the product datasheet

Order the XL Cytokine Discovery Panel

 

Analytes Available from the Human XL Cytokine Discovery Panel

Click on the linked analytes to view performance data compared to other suppliers.

CD40 Ligand IL-1 beta IL-33
EGF IL-1ra IP-10/CXCL10
Eotaxin/CCL11 IL-2 MCP-1/CCL2
FGF basic/FGF-2 IL-3 MIP-1 alpha/CCL3
Flt-3 Ligand IL-4 MIP-1 beta/CCL4
Fractalkine/CX3CL1 IL-5 MIP-3 alpha/CCL20
G-CSF IL-6 MIP-3 beta/CCL19
GM-CSF IL-7 PD-L1/B7-H1
Granzyme B IL-8/CXCL8 PDGF-AA
GRO alpha/CXCL1 IL-10 PDGF-BB
GRO beta/CXCL2 IL-12 p70 RANTES/CCL5
IFN-alpha IL-13 TGF-alpha
IFN-beta IL-15 TNF-alpha
IFN-gamma IL-17A TRAIL
IL-1 alpha IL-17E/IL-25 VEGF

Get Performance and Results You Can Trust

The XL Cytokine Discovery Luminex High Performance Assay outperformed other suppliers’ assays when tested for linearity of dilution, a common method for assessing assay accuracy. The results for IL-2 are shown below; click here to see more data.

R&D Systems vs Supplier M
R&D Systems vs Supplier B

Get Superior Accuracy with the Human XL Cytokine Discovery Luminex® Performance Assay

Our assay development is second to none, and we’ve proven this again by testing our new Human XL Cytokine Discovery Panel side by side with panels from three other Luminex suppliers. We tested for linearity of dilution, a common method for assessing assay accuracy, and our XL Cytokine Discovery Panel outperformed other suppliers' assays using serum, plasma, or both for every analyte shown below.

Linearity of Dilution

Accurate assays yield a straight line on the graphs below at or near 100% because the analyte being measured is accurately detected as samples are diluted. If the line deviates far from 100% as samples are diluted, this is an indicator that the assay is not accurately measuring the analyte of interest. For this study, a known concentration of the appropriate recombinant protein was spiked into serum or plasma and assayed by three-fold serial dilutions for each XL Cytokine Discovery Luminex Performance Assay and for each supplier Luminex assay.* Sample values were back-calculated based on the standard curve, normalized to the initial sample dilution, and represented as % recovery vs. sample dilution. Remember, a straight line equals an accurate assay!

*When one or more suppliers are absent for an analyte below this is because the supplier's panel did not include that analyte, we were unable to generate data with that kit, or the performance was comparable to the XL Cytokine Discovery Panel.

Click on the graphs for a larger image.

FGF basic/FGF-2

R&D Systems vs Supplier M
FGF-Basic/FGF-2
R&D Systems vs Supplier B
FGF-Basic/FGF-2
 

Flt-3 Ligand

R&D Systems vs Supplier M
Flt-3 Ligand
 


Note - the data collected for the 1:27 dilution in plasma with Supplier B's kit fell outside the standard curve range and was not included.

 

GM-CSF

R&D Systems vs Supplier M
GM-CSF
 
 

IFN-alpha

R&D Systems vs Supplier M
IFN-alpha
R&D Systems vs Supplier T
IFN-alpha
 

IL-2

R&D Systems vs Supplier M
IL-2
R&D Systems vs Supplier B
IL-2
 
R&D Systems vs Supplier T
IL-2
 
 

IL-5

R&D Systems vs Supplier M
IL-5
R&D Systems vs Supplier B
IL-5
 
R&D Systems vs Supplier T
IL-5
 
 

IL-7

R&D Systems vs Supplier B
IL-17
R&D Systems vs Supplier T
IL-17
 

IL-10

R&D Systems vs Supplier M
IL-10
R&D Systems vs Supplier B
IL-10
 
R&D Systems vs Supplier T
IL-10
 
 

IL-12 p70

R&D Systems vs Supplier M
IL-12-p70
R&D Systems vs Supplier B
IL-12-p70
 
R&D Systems vs Supplier T
IL-12-p70
 
 

IL-13

R&D Systems vs Supplier M
IL-13
R&D Systems vs Supplier B
IL-13
 

IL-15

R&D Systems vs Supplier M
IL-15
R&D Systems vs Supplier B
IL-15


Note - the data collected for the 1:27 dilution in plasma with Supplier B's kit fell outside the standard curve range and was not included.

 

IL-17A

R&D Systems vs Supplier M
IL-17a
R&D Systems vs Supplier B
IL-17a
 
R&D Systems vs Supplier T
IL-17a
 
 

MCP-1/CCL2

R&D Systems vs Supplier M
MCP-1
R&D Systems vs Supplier B
MCP-1
 

MIP-1 beta/CCL4

R&D Systems vs Supplier M
MIP beta
R&D Systems vs Supplier B
MIP beta
 
R&D Systems vs Supplier T
MIP beta
 
 

RANTES/CCL5

R&D Systems vs Supplier M
RANTES/CCL5
R&D Systems vs Supplier T
RANTES/CCL5
 

TGF-alpha

R&D Systems vs Supplier M
TGF Alpha