IGF-I R/IGF1R Antibody Blocking Peptide

Novus Biologicals | Catalog # NBP1-77679PEP

Novus Biologicals
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Key Product Details

Applications

Antibody Competition
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Product Specifications

Application Notes

This peptide is useful as a blocking peptide for NBP1-77679. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NBP1-77679 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NBP1-77679PEP
Formulation Peptide dissolved in dH20. Contains no BSA.
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: IGF-I R/IGF1R

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Long Name

Insulin-like Growth Factor I Receptor

Alternate Names

CD221, IGF-1R, IGF-IR, IGF1R, IGFIR

Gene Symbol

IGF1R

Additional IGF-I R/IGF1R Products

Product Documents for IGF-I R/IGF1R Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for IGF-I R/IGF1R Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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