High affinity, selective CB2
receptor agonist (Ki
values are 6.4 and 1043 nM for CB2
receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB2
receptors expressed in CHO cells (EC50
= 8.1 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630.
Ross et al.
3-(1',1'-dimethylbutyl)-1-deoxy-D8-THC and related compounds: synthesis of selective ligands for the CB2 receptor.
Huffman et al.
The search for selective ligands for the CB2 receptor.