Highly selective CB2
receptor agonist (Ki
values are 11.8 and 4888 nM for CB2
receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB2
receptors expressed in CHO cells (EC50
= 3.1 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630.
Ross et al.
CB2 receptor ligands.
Mini Rev.Med.Chem., 2005;5:641
The search for selective ligands for the CB2 receptor.