Catalog Number: 2235
Biological Activity
Novel phosphopeptide derived from GSK-3 recognition motif that acts as a substrate-competitive inhibitor of GSK-3β (IC50 = 150 μM). Displays minimal inhibition of Cdc2, MAPK, PKA, CK2, PKCδ and PKB at 200 μM.
Technical Data
  • M.Wt:
    1198.23
  • Formula:
    C50H80N13O19P
  • Sequence:
    KEAPPAPPQSP

    (Modifications: Ser-10 = pSer)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    348089-28-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under licence from Tel Aviv University Future Technology LP
Background References
  1. Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3.
    Plotkin et al.
    J.Pharmacol.Exp.Ther., 2003;305:974

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