Novel phosphopeptide derived from GSK-3 recognition motif that acts as a substrate-competitive inhibitor of GSK-3β
= 150 μ
M). Displays minimal inhibition of Cdc2, MAPK, PKA, CK2, PKCδ
and PKB at 200 μ
M. Myristoylated version available (L803-mts
, Cat. No. 2256).
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All Tocris products are intended for laboratory research use only.
Sold under licence from Tel Aviv University Future Technology LP
Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3.
Plotkin et al.