Catalog Number: 5387
Chemical Name: 1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol
Biological Activity
Selective PAR4 antagonist (IC50 = 140 nM). Exhibits 70-fold selectivity for PAR4 over PAR1.
Technical Data
  • M.Wt:
    282.29
  • Formula:
    C16H14N2O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    89159-60-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Substituted indoles as selective protease activated receptor 4 (PAR4) antagonists: Discovery and SAR of ML354.
    Wen et al.
    Bioorg.Med.Chem.Lett., 2014;24:4708

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