Catalog Number: 1926
Alternate Names: Myosin Light Chain Kinase Inhibitor
Biological Activity
Competitive myosin light chain kinase (MLCK) inhibitor (Ki = 1 - 2.2 mM); derived from the calmodulin binding site of skeletal muscle MLCK. Also inhibits calmodulin.
Technical Data
  • M.Wt:
    1444.79
  • Formula:
    C68H113N23O12
  • Sequence:
    KRRWKKNFIAV

    (Modifications: Val-11 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    198694-74-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence.
    Kemp et al.
    J.Biol.Chem., 1987;262:2542

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