Mouse C1q R1/CD93 PE-conjugated Antibody

FAB1696P has been discontinued. View all C1q R1/CD93 products.
    
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  • Species Reactivity
    Mouse
  • Specificity
    Detects mouse C1q R1/CD93 in direct ELISAs.
  • Source
    Monoclonal Rat IgG2B Clone # 223437
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    Mouse myeloma cell line NS0-derived recombinant mouse C1q R1/CD93
    Ala23-Asn572
    Accession # O89103
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Phycoerythrin
Product Datasheets

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Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example
Detection of C1q R1/CD93 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse C1q R1/CD93 PE‑conjugated Monoclonal Antibody (Catalog # FAB1696P, filled histogram) or isotype control antibody (Catalog # IC013P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: C1q R1/CD93

Complement component 1, q subcomponent receptor (C1q R1), also known as C1q Rp, Collectin receptor and AA4 antigen in rodents, mediates enhanced phagocytosis by monocytes and macrophages upon interaction with soluble defense collagens including C1q, MBL (mannose-binding lectin) and SP-A (pulmonary surfactant protein A) (1, 2). It is a type I transmembrane glycoprotein expressed on endothelial cells, hematopoietic progenitor cells, platelets and cells of myeloid origin. C1q R1 has also been identified as a stem cell marker (3, 4).

  • References:
    1. Kim, T.S. et al. (2000) Mol. Immunol. 37:377.
    2. Dean, Y.D. et al. (2001) Eur. J. Immunol. 31:1370.
    3. Petrenko, O. et al. (1999) Immunity 10:691.
    4. Danet, G.H. et al. (2002) Proc. Natl. Acad. Sci. USA 99:1044.
  • Long Name:
    Complement Component C1q Receptor
  • Entrez Gene IDs:
    22918 (Human); 17064 (Mouse); 84398 (Rat)
  • Alternate Names:
    AA4 Antigen; C1q R1; C1q receptor 1; C1q Rp; C1q/MBL/SPA receptor; C1qR(P); C1qR1; C1qRp; CD93 antigenC1qR; CD93 molecule; CD93; CDw93C1QR1; Collectin Receptor; Complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; Matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4
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