Mouse CD200 R3 PE-conjugated Antibody

FAB6554P has been discontinued. View all CD200 R3 products.
  
  • Species Reactivity
    Mouse
  • Specificity
    Detects mouse CD200 R3 in flow cytometry.
  • Source
    Polyclonal Sheep IgG
  • Purification
    Antigen Affinity-purified
  • Immunogen
    Mouse myeloma cell line NS0-derived recombinant mouse CD200 R3
    Ser26-Ser245
    Accession # Q5UKY4
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Phycoerythrin
Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of CD200 R3 in MC/9‑2 Mouse Cell Line by Flow Cytometry. MC/9‑2 mouse mast cell line was stained with Sheep Anti-Mouse CD200 R3 PE‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB6554P, filled histogram) or isotype control antibody (Catalog # IC016P, open histogram). View our protocol for Staining Membrane-associated Proteins
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD200 R3
Mouse CD200 R3, also known as CD200RLb, is a 38-40 kDa type I transmembrane glycoprotein member of a small family of CD200R-related molecules. Family members named CD200R1-5 represent activating counterparts to CD200R that is a widely expressed inhibitory receptor for the ligand CD200. Consistent with other family members, CD200 R3 is a Ig-superfamily member with a V-type and C2-type Ig-like domain. But unlike other family members, it presents as a disulfide-linked homodimer that is highly spliced, poorly glycosylated, and shows an unusual modification of its C2-type Ig-like domain. It is expressed by mast cells, basophils, and CD49+ regulatory dendritic cells. It does not bind CD200. When experimentally activated, it induces IL-4 production and degranulation. There is no direct human or rat counterpart to mouse CD200 R3.
  • Long Name:
    CD200 Receptor 3
  • Entrez Gene IDs:
    74603 (Mouse)
  • Alternate Names:
    CD200 R3; CD200R3; CD200RLb
Related Research Areas

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