Mouse Complement Component C1rLP Alexa Fluor® 405-conjugated Antibody

Catalog #: AF3990V Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3990V-100UG

All Complement Component C1rLP Antibodies

Product Details

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Complement Component C1rLP Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Complement Component C1rLP in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross‑reactivity with recombinant human (rh) C1rLP is observed and less than 1% cross‑reactivity with rh

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Complement Component C1rLP
Ser18-Asp456
Accession # AAP41417

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Complement Component C1rLP

Mouse C1rLP, also CLSPa, is a 55 kDa, secreted, atypical glycoprotein member of the AGY group of servine proteases. It has protease activity for pro-haptoglobin, but accomplishes cleavage without a typical Asp in the catalytic site. In addition, it is proposed to block unwanted complement-mediated proteolysis. Mature C1rLP is 443 amino acids (aa) in length. It contains one CUB domain (aa 43‑165), a truncated CCP2 region (aa 167‑223) and a serine protease domain (aa 239‑482). There is a potential short form that utilizes an alternate start site at Met 27. Over aa 44‑456, mouse C1rLP is 78% and 90% aa identical to human and rat C1rLP, respectively.

Long Name

Complement C1r Subcomponent-like Protein

Entrez Gene IDs

51279 (Human); 232371 (Mouse)

Alternate Names

C1RL; C1RL1; C1RL1complement C1r subcomponent-like protein; C1r-like protein; C1r-like serine protease analog protein; C1r-LPcomplement C1r-like proteinase; C1RLPEC 3.4.21.-; CLSPa; complement component 1, r subcomponent-like; Complement Component C1rLP; EC 3.4.21; EC 3.4.21.41