Mouse IL-31 (NP_083870) VersaClone cDNA
Mouse IL-31 (NP_083870) VersaClone cDNA Summary
Interleukin 31 (IL-31) is a secreted, T-cell-derived, 24-kDa, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.
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