Mouse Integrin  alpha 5/CD49e PE-conjugated Antibody

FAB1754P has been discontinued. View all Integrin alpha 5/CD49e products.
  • Species Reactivity
  • Specificity
    Detects mouse Integrin alpha 5/CD49e in direct ELISAs and Western blots.
  • Source
    Monoclonal Rat IgG2B Clone # 235112
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    Mouse myeloma cell line NS0-derived recombinant mouse Integrin alpha 5/CD49e
    Phe45-Asn999 (Gln68Glu)
    Accession # P11688
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of Integrin  alpha 5/CD49e in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse Integrin  alpha 5/CD49e PE‑conjugated Monoclonal Antibody (Catalog # FAB1754P, filled histogram) or isotype control antibody (Catalog # IC013P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Integrin alpha 5/CD49e
Integrin alpha 5 subunit, also called CD49e, associates with the Integrin beta 1 subunit (CD29) to form the VLA-5 complex. It is expressed on thymocytes, mast cells, activated T lymphocytes, and some mouse cell lines. It functions as a receptor for fibronectin (1‑4).
  • References:
    1. Springer, T.A. et al. (1982) Immunol. Rev. 68:171.
    2. Kinashi, T. and T.A. Springer (1994) Blood Cells 20:25.
    3. Halvorson, M.J. et al. (1995) J. Immunol. 55:4567.
    4. Uhlenkott, E.C. et al. (1996) Clin. Exp. Metastasis 14:125.
  • Entrez Gene IDs:
    3678 (Human); 16402 (Mouse)
  • Alternate Names:
    CD49 antigen-like family member E; CD49e antigen; CD49e; Fibronectin receptor subunit alpha; fibronectin receptor, alpha subunit; FNRAVLA5A; Integrin alpha 5; integrin alpha-5; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5; very late activation protein 5, alpha subunit; VLA-5 alpha; VLA-5
Related Research Areas

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