Detection of Integrin alpha 5/CD49e in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse Integrin alpha 5/CD49e PE‑conjugated Monoclonal Antibody (Catalog # FAB1754P, filled histogram) or isotype control antibody (Catalog # IC013P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Background: Integrin alpha 5/CD49e
Integrin alpha 5 subunit, also called CD49e, associates with the Integrin beta 1 subunit (CD29) to form the VLA-5 complex. It is expressed on thymocytes, mast cells, activated T lymphocytes, and some mouse cell lines. It functions as a receptor for fibronectin (1‑4).
Springer, T.A. et al. (1982) Immunol. Rev. 68:171.
Kinashi, T. and T.A. Springer (1994) Blood Cells 20:25.
Halvorson, M.J. et al. (1995) J. Immunol. 55:4567.
Uhlenkott, E.C. et al. (1996) Clin. Exp. Metastasis 14:125.
Entrez Gene IDs:
3678 (Human); 16402 (Mouse)
CD49 antigen-like family member E; CD49e antigen; CD49e; Fibronectin receptor subunit alpha; fibronectin receptor, alpha subunit; FNRAVLA5A; Integrin alpha 5; integrin alpha-5; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5; very late activation protein 5, alpha subunit; VLA-5 alpha; VLA-5
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