Mouse KLRG1 Alexa Fluor® 594-conjugated Antibody

FAB69441T Datasheet / COA / SDS

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FAB69441T-100UG

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Mouse KLRG1 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse KLRG1 in direct ELISAs.

Source

Monoclonal Hamster IgG Clone # 2F1

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

IL-2 activated NK cells from C57/BL6 mice
Accession # O88713

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

0.25-1 µg/10⁶ cells

Mouse splenocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: KLRG1

KLRG1 (killer cell lectin-like receptor G1), also called MAFA (mast cell function associated), is a 30-38 kDa type II transmembrane inhibitory glycoprotein of the C-type lectin family, designated CLEC15A. KLRG1 binds E-, N- and R-cadherins and functions as an MHC-independent means of identifying non-self pathogens and epithelial tumor cells with low E-cadherin expression. It is expressed as a monomer or disulfide-linked homodimer on NK and T cell subsets such as tumor-infiltrating lymphocytes.

Long Name

Killer Cell Lectin-like Receptor Subfamily G Member 1

Entrez Gene IDs

10219 (Human); 50928 (Mouse); 58975 (Rat)

Alternate Names

2F1; CLEC15A; CLEC15AMAFA-LIKE; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; KLRG1; MAFA; MAFAL; MAFA-L; MAFA-like receptor; MAFAMAFA-2F1; mast cell function-associated antigen (ITIM-containing); Mast cell function-associated antigen; MGC13600