High affinity D4
receptor ligand; selective over D1
receptors. Displays antagonist activity at the human D4.2
= 3.6 nM in transfected CHO cells) and exhibits agonist activity at the D4.4
receptor in HEK 293 cells.
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NGD 94-1 as an agonist at human recombinant dopamine D4.4 receptors expressed in HEK293 cells.
Gazi et al.
I. NGD 94-1: Identification of a novel, high affinity antagonist at the human dopamine D4 receptor.
Tallman et al.
II. Localization and characterization of dopamine D4 binding sites in rat and human brain by use of the novel, D4 receptor-selective ligand [3H]NGD 94-1.
Primus et al.