Catalog Number: 4035
Chemical Name: N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-glycine lithium salt
Biological Activity
Selective inhibitor of the glial glycine transporter (GlyT1) (pIC50 values are 6.9, <4 and <3 for GlyT1, GABA transporter and Glyt2 respectively).
Technical Data
  • M.Wt:
    373.3
  • Formula:
    C19H19F3LiNO3
  • Solubility:
    Soluble to 10 mM in water and to 5 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    722456-08-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Role of glial and neuronal glycine transporters in the control of glycinergic and glutamatergic synaptic transmission in lamina X of the rat spinal cord.
    Bradaia et al.
    J.Physiol., 2004;559:169
  2. The time course of transmitter at glycinergic synapses onto motoneurons.
    Beato
    J.Neurosci., 2008;28:7412

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