[Orn5]-URP
![[Orn5]-URP](http://resources.rndsystems.com/images/datasheets/tocris/3162.png "[Orn5]-URP")
Biological Activity
Urotensin-II (UT) receptor pure antagonist (pEC50 = 7.24). Displays no agonist activity unlike other U-II/URP analogs. Inhibits the action of U-II in the rat aorta ring assay.Technical Data
(Modifications: X = Orn, Disulfide bridge between 2 - 7)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Structure-activity relationships and structural conformation of a novel urotensin II-related peptide.
Chatenet et al.
Peptides, 2004;25:1819 -
[Orn5]URP acts as a pure antagonist of urotensinergic receptors in rat cortical astrocytes.
Diallo et al.
Peptides, 2008;29:813
Product Datasheets
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Citation for [Orn5]-URP
The citations listed below are publications that use Tocris products. Selected citations for [Orn5]-URP include:
1 Citation: Showing 1 - 1
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Urotensin II induces interleukin 8 expression in human umbilical vein endothelial cells.
Authors: Lee Et al.
PLoS One 2014;9:e90278
FAQs
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