Catalog Number: 2094
Alternate Names: Glucagon (1-37), Enteroglucagon
Biological Activity
Endogenous glucagon-like peptide that modulates feeding and metabolism; secreted by intestinal L-cells. Increases cAMP production and inhibits gastric acid secretion in rat stomach. Also inhibits intestinal glucose absorption. Reduces fasting ghrelin levels following peripheral administration and reduces food intake and weight gain in rats following central or peripheral administration in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Bioactive enteroglucagon (oxyntomodulin): present knowledge on its chemical structure and its biological activities.
    Bataille et al.
    Peptides, 1981;2:41
  2. A new role for enteric glucagon-37: acute stimulation of glucose absorption in rat small intestine.
    Stumpel et al.
    FEBS Lett., 1997;410:515
  3. Peripheral oxyntomodulin reduces food intake and body weight gain in rats.
    Dakin et al.
    Endocrinology, 2004;145:2687
  4. Gastrointestinal satiety signals III. Glucagon-like peptide 1, oxyntomodulin, peptide YY, and pancreatic polypeptide.
    Stanley et al.
    Am.J.Physiol.Gastrointest.Liver Physiol., 2004;286:G693
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