P11

Catalog # Availability Size / Price Qty
4744/1
Cat.No. 4744 - P11 | His-Ser-Asp-Val-His-Lys-NH2 | CAS No. 848644-86-0
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Description: Potent antagonist of αvβ3-vitronectin interaction; antiangiogenic
Product Details
Citations (1)
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Biological Activity

Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.

Technical Data

M.Wt:
720.78
Formula:
C30H48N12O9
Sequence:
HSDVHK

(Modifications: Lys-6 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in 20% acetonitrile - 0.1% acetic acid
Storage:
Store at -20°C
CAS No:
848644-86-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for P11

The citations listed below are publications that use Tocris products. Selected citations for P11 include:

1 Citation: Showing 1 - 1

  1. Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3.
    Authors: Visavadiya
    Cell Communication and Signaling  2016;14:32

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