Potent, selective non-peptidic neuropeptide Y1
receptor antagonist (Ki
= 48 nM); selective over Y2
> 10 μ
M). Antagonizes NPY-mediated inhibition of cAMP accumulation in SK-N-MC cells (IC50
= 8.2 nM).
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All Tocris products are intended for laboratory research use only.
8-Amino-6-(arylsulphonyl)-5-nitroquinolines: novel nonpeptide neuropeptide Y1 receptor antagonists.
Wright et al.
The citations listed below are publications that use Tocris products. Selected citations for PD 160170 include:
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