PMX 464

Catalog # Availability Size / Price Qty
4996/10
4996/50
Cat.No. 4996 - PMX 464 | C13H9NO2S | CAS No. 485842-97-5
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Description: Putative inhibitor of the Trx-TrxR system; antiproliferative

Chemical Name: 4-(2-Benzothiazolyl)-4-hydroxy-2,5-cyclohexadien-1-one

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Putative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system. Shown to inhibit Trx and induce a G1/S block in HT29 cells; inhibits cell proliferation in various colorectal cancer cell lines and MCF7 cells. Also elicits an anti-inflammatory response in A549 cells.

Technical Data

M.Wt:
243.28
Formula:
C13H9NO2S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
485842-97-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for PMX 464

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