PP2A alpha Antibody (H5D12) - BSA Free

Novus Biologicals | Catalog # NBP2-29818

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # H5D12

Format

BSA Free
View all PP2A Primary Antibodies »

Product Specifications

Immunogen

GST fusion protein corresponding to the N-terminus of human PP2A, B subunit, B56 delta.

Reactivity Notes

Human

Specificity

Human PP2A, B subunit, B56 delta. This monoclonal antibody is the delta isoform for the B56 family of protein phosphatase 2A.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Relevant Entrez Gene Numbers: NM_006245

Scientific Data Images for PP2A alpha Antibody (H5D12) - BSA Free

Western Blot: PP2A alpha Antibody (H5D12)BSA Free [NBP2-29818]

Western Blot: PP2A alpha Antibody (H5D12)BSA Free [NBP2-29818]

Western Blot: PPP2R4 Antibody (H5D12) [NBP2-29818] - This lot detected PP2A, B subunit, B56 delta in HeLa nuclear cell extract when it was tested at 1:2000 in blocking buffer.

Applications for PP2A alpha Antibody (H5D12) - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PP2A

PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Balpha, Bbeta and Bgamma. The B' (or B56) family consists of at least seven splice variantsderived from five genes. RNA's for the two members of the B'' family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals.

Alternate Names

PP2CA, PPP2CA, RP-C

Gene Symbol

PPP2CA

UniProt

Q14738 (Human)

Additional PP2A Products

Product Documents for PP2A alpha Antibody (H5D12) - BSA Free

Certificate of Analysis

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Product Specific Notices for PP2A alpha Antibody (H5D12) - BSA Free

Relevant Entrez Gene Numbers: NM_006245

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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Associated Pathways

TGF-beta Signaling Pathways TGF-beta Signaling Pathway Thumbnail