Catalog Number: 1923
Biological Activity
Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Tyr-7 = pTyr)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides.
    Harder et al.
    Biochem.J., 1994;298:395
  2. Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxy terminus of pp60c-src.
    Roussel et al.
    Proc.Natl.Acad.Sci.U.S.A., 1991;88:10696
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