PQ 401

  ( 5 citations )    
Product Datasheet
Catalog Number:2768
Chemical Name:N-(5-Chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)urea
Product Details
Citations (5)
Reviews
Biological Activity
Insulin-like growth factor receptor (IGF1R) inhibitor. Suppresses IGF-stimulated IGF-IR autophosphorylation with an IC50 value of 12 μM. Inhibits growth of MCF-7 breast cancer cells in vitro and in vivo.
Technical Data
  • M.Wt:
    341.79
  • Formula:
    C18H16ClN3O2
  • Solubility:
    Soluble to 50 mM in DMSO and to 25 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    196868-63-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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