Catalog Number: 3353
Chemical Name: 4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridine hydrochloride
Biological Activity
GPR119 receptor agonist (EC50 values are 8.4 and 7.9 μM at human and mouse receptors respectively). Displays similar potency to the endogenous ligand oleylethanolamide (OEA) (Cat. No. 1484).
Technical Data
  • M.Wt:
    321.84
  • Formula:
    C17H23N3O.HCl
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    388575-52-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents.
    Overton et al.
    Cell Metab., 2006;3:167
  2. Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells.
    Ning et al.
    Br.J.Pharmacol., 2008;155:1056

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