PSN 375963 hydrochloride
Chemical Name: 4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridine hydrochloride
Biological ActivityGPR119 receptor agonist (EC50 values are 8.4 and 7.9 μM at human and mouse receptors respectively). Displays similar potency to the endogenous ligand oleylethanolamide (OEA) (Cat. No. 1484).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents.
Overton et al.
Cell Metab., 2006;3:167
Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on Ins secretion in MIN6c4 Insoma cells.
Ning et al.
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