(R)-(+)-8-Hydroxy-DPAT hydrobromide

  ( 3 citations )    
Product Datasheet
Catalog Number:1080
Chemical Name:(2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide
Product Details
Citations (3)
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Biological Activity
Full 5-HT1A serotonin receptor agonist. Reduces hippocampal 5-HT levels following systemic administration in rats in vivo. More active enantiomer of 8-Hydroxy-DPAT hydrobromide.

Racemate and 7-Hydroxy Isomer also available.

Technical Data
  • M.Wt:
    328.29
  • Formula:
    C16H25NO.HBr
  • Solubility:
    Soluble to 75 mM in water and to 75 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    78095-19-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (R)-(+)-8-Hydroxy-DPAT hydrobromide include:

3 Citations: Showing 1 - 3
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  1. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A.
    Authors: Cassilly Et al.
    Psychopharmacology (Berl)  2016;11:e0154932
  2. The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies.
    Authors: Wierońska Et al.
    Oncoscience  2015;232:259
  3. Differential regulation of serotonin-1A receptor-stimulated [35S]GTP gamma S binding in the dorsal raphe nucleus by citalopram and escitalopram.
    Authors: Rossi Et al.
    Eur J Pharmacol  2008;583:103

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