Catalog Number: 1095
Alternate Names: Selegiline
Chemical Name: (R)-(-)-N-α-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride
Biological Activity
Selective inhibitor of monoamine oxidase B (MAO-B).
Technical Data
  • M.Wt:
    223.74
  • Formula:
    C13H17N.HCl
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    14611-52-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Effect of selegeline on dopamine concentration in the striatum of a primate.
    Kaseda et al.
    Brain Res., 1999;815:44
  3. The molecular pharmacology of L-deprenyl.
    Gerlach et al.
    Eur.J.Pharmacol., 1992;226:97
  4. Deprenyl decreases an endogenous parkinsonism-inducing compound, 1-benzyl-1,2,3,4-tetrahydroisoquinoline in mice: in vivo and in vitro studies.
    Kotake et al.
    Brain Res., 1998;787:341
  5. Modification of levodopa responses by deprenyl (selegiline): an electrophysiological and behavioural study in the rat relevant to Parkinson's disease.
    Mercuri et al.
    Ann.Neurol., 1998;43:613

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