(R)-(-)-Ketamine hydrochloride New
Chemical Name: (R)-(-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride
Biological ActivityNMDA antagonist (Ki = 1.4 μM); exhibits more potent and longer lasting antidepressant effects compared to its enantiomer (S)-ketamine in vivo. Also may not display the psychotomimetic or addictive side effects associated with (S)-ketamine.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
R-(-)-ketamine shows greater potency and longer lasting antidepressant effects than S-(+)-ketamine.
Zhang et al.
Comparison of rapid and long-lasting antidepressant effects of negative modulators of α5-containing GABAA receptors and (R)-ketamine in a chronic social defeat stress model.
Xiong et al.
NMDAR inhibition-independent antidepressant actions of ketamine metabolites.
Zanos et al.
Norketamine, the main metabolite of ketamine, is a non-competitive NMDA receptor antagonist in the rat cortex and spinal cord.
Ebert et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for (R)-(-)-Ketamine hydrochloride
There are currently no reviews for this product. Be the first to review (R)-(-)-Ketamine hydrochloride and earn rewards!
Have you used (R)-(-)-Ketamine hydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image