(R)-(-)-Rolipram

  ( 1 citations )    
Product Datasheet
Catalog Number:1349
Chemical Name:(4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
Product Details
Citations (1)
Reviews
Biological Activity
More active enantiomer of the PDE4 inhibitor rolipram; 2-10-fold more potent than the S-(+) enantiomer.

Available as part of the Phosphodiesterase Inhibitor Tocriset™. Racemate and S-enantiomer also available.

Technical Data
  • M.Wt:
    275.35
  • Formula:
    C16H21NO3
  • Solubility:
    Soluble to 100 mM in ethanol and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    85416-75-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (R)-(-)-Rolipram include:

1 Citations: Showing 1 - 1

  1. Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model.
    Authors: Boomkamp Et al.
    Br J Pharmacol  2014;171:2385

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