Rat Hepassocin/FGL1 Biotinylated Affinity Purified PAb

Catalog # Availability Size / Price Qty
BAF1105
Product Details
Citations (2)
FAQs
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Rat Hepassocin/FGL1 Biotinylated Affinity Purified PAb Summary

Species Reactivity
Rat
Specificity
Detects rat Hepassocin in Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant rat Hepassocin
Met1-Val314
Accession # Q5M8C6
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Rat Hepassocin
Immunohistochemistry
5-15 µg/mL
Perfusion fixed frozen sections of rat liver

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Hepassocin/FGL1

Hepassocin, also known as fibrinogen like 1 (FGL1) and hepatocyte-derived fibrinogen-related protein 1 (HFREP1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. Hepassocin/FGL1 may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin/FGL1 is upregulated during liver regeneration following partial hepatectomy.

Long Name
Fibrinogen Like 1
Entrez Gene IDs
2267 (Human); 246186 (Rat); 102118020 (Cynomolgus Monkey)
Alternate Names
FGL1; fibrinogen-like 1; fibrinogen-like protein 1; Fibrinogen-like-protein 1; FREP1; Hepassocin; hepatocellular carcinoma-related sequence; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; HFREP1MGC12455; HP-041; LFIRE1; LFIRE-1; Liver fibrinogen-related protein 1

Product Datasheets

Citations for Rat Hepassocin/FGL1 Biotinylated Affinity Purified PAb

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Elevated plasma level of soluble F11 receptor/junctional adhesion molecule-A (F11R/JAM-A) in hypertension.
    Authors: Ong KL, Leung RY, Babinska A, Salifu MO, Ehrlich YH, Kornecki E, Wong LY, Tso AW, Cherny SS, Sham PC, Lam TH, Lam KS, Cheung BM
    Am. J. Hypertens., 2009;22(5):500-5.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Development
  2. Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant.
    Authors: Liu Z, Ukomadu C
    Biochem. Biophys. Res. Commun., 2007;365(4):729-34.
    Species: Rat
    Sample Types: Serum
    Applications: ELISA Development

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