Catalog Number: 0894
Chemical Name: (RS)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
Biological Activity
Standard D2-like dopamine receptor antagonist. (S)-(-)-Sulpiride (Cat. No. 0895) also available.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in 1eq. HCl with gentle warming and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Dopamine receptor pharmacology.
    Seeman and Van Tol
    Trends Pharmacol.Sci., 1994;15:264
  3. Dopamine D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective.
    Seeman and Van Tol
    Eur.J.Pharmacol., 1993;233:173

The citations listed below are publications that use Tocris products. Selected citations for (RS)-(±)-Sulpiride include:

Showing Results 1 - 3 of 3

  1. Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues.
    Authors: Holroyd Et al.
  2. Sucrose produces withdrawal and dopamine-sensitive reinforcing effects in planarians.
    Authors: Zhang Et al.
    Physiol Behav
  3. Exposure to extremely low frequency magnetic fields induces fos-related antigen-immunoreactivity via activation of dopaminergic d1 receptor.
    Authors: Shin Et al.
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