Catalog Number: 0894
Chemical Name: (RS)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
Biological Activity
Standard D2-like dopamine receptor antagonist.

S-enantiomer also available.

Technical Data
  • M.Wt:
    341.42
  • Formula:
    C15H23N3O4S
  • Solubility:
    Soluble to 50 mM in 1eq. HCl with gentle warming and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    15676-16-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Dopamine receptor pharmacology.
    Seeman and Van Tol
    Trends Pharmacol.Sci., 1994;15:264
  3. Dopamine D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective.
    Seeman and Van Tol
    Eur.J.Pharmacol., 1993;233:173
Citations:

The citations listed below are publications that use Tocris products. Selected citations for (RS)-(±)-Sulpiride include:

3 Citations: Showing 1 - 3
Filter your results:

  1. Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues.
    Authors: Holroyd Et al.
    Brain 2015;40:1495
  2. Sucrose produces withdrawal and dopamine-sensitive reinforcing effects in planarians.
    Authors: Zhang Et al.
    Physiol Behav 2013;112-113:8
  3. Exposure to extremely low frequency magnetic fields induces fos-related antigen-immunoreactivity via activation of dopaminergic d1 receptor.
    Authors: Shin Et al.
    Neuropsychopharmacology 2011;20:130

Have you used (RS)-(±)-Sulpiride?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information