Catalog Number: 2970
Chemical Name: (7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid γ-lactone
Biological Activity
Mineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 25 mM in DMSO
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats.
    Kalimi et al.
    Am.J.Physiol., 1990;258:E737
  2. Structural basis of spirolactone recognition by the mineralocorticoid receptor.
    Huyet et al.
    Mol.Pharmacol., 2007;72:563
  3. Evidence for an antagonist specific receptor that does not bind mineralocorticoid agonists.
    Lazar and Agarwal
    Biochem.Biophy.Res.Comms., 1986;134:261
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information