Catalog Number: 3935
Chemical Name: 5-(6,7-Dihydrobenzo[b]thien-4-yl-1H-imidazole hydrochloride
Biological Activity
Agonist of the α2D adrenergic receptor (Ki values are 1.5, 254, 443 and 621 nM for α2D, α2A, α1 and α2B adrenergic receptors respectively).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO and to 50 mM in ethanol
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibitory and facilitatory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human α1- and α2-adrenoceptor subtypes.
    Amphoux et al.
    Eur.J.Pharmacol., 2010;634:1
  2. α2 adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene as a high-affinity ligand for the α2D adrenergic receptor.
    Ross et al.
    J.Med.Chem., 2000;43:765
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