Chemical Name: 5-(6,7-Dihydrobenzo[b]thien-4-yl-1H-imidazole hydrochloride
Biological ActivityRWJ 52353 is a agonist of the α2D adrenergic receptor (Ki values are 1.5, 254, 443 and 621 nM for α2D, α2A, α1 and α2B adrenergic receptors respectively).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
α2 adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene as a high-affinity ligand for the α2D adrenergic receptor.
Ross et al.
Inhibitory and facilitatory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human α1- and α2-adrenoceptor subtypes.
Amphoux et al.
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