(S)-(-)-Bay K 8644

  ( 4 citations )    
Product Datasheet
Catalog Number:1546
Chemical Name:(4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester
Product Details
Citations (4)
Reviews
Biological Activity
L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo.

Racemate and (R)-(+)-Enantiomer also available.

Technical Data
  • M.Wt:
    356.3
  • Formula:
    C16H15F3N2O4
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    98625-26-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (S)-(-)-Bay K 8644 include:

4 Citations: Showing 1 - 4
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  1. Inhibition of late sodium current suppresses calcium-related ventricular arrhythmias by reducing the phosphorylation of CaMK-II and sodium channel expressions.
    Authors: Wei Et al.
    Sci Rep  2017;7:981
  2. Spectrum of Cav1.4 dysfunction in congenital stationary night blindness type 2.
    Authors: Burtscher Et al.
    Biochim Biophys Acta  2014;1838:2053
  3. Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling.
    Authors: Landstrom Et al.
    Eneuro  2011;4:214
  4. Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.
    Authors: Chen Et al.
    Nat Neurosci  2011;14:570

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