Enantiomer that is a subtype-selective M2
muscarinic receptor antagonist (pKi
values are 7.08, 7.78, 6.70 and 7.00 for M1
receptors respectively). Also H1
histamine receptor antagonist (pKi
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Neuronal soma-dendritic and prejunctional M1-M4 receptors in gastrointestinal and genitourinary smooth muscle.
Lambrecht et al.
Life Sci., 1999;64:403
The (S)-(+)-enantiomer of dimethindene: a novel M2-selective muscarinic receptor antagonist.
Pfaff et al.