Chemical Name: (S)-(+)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride
Biological ActivityNMDA receptor antagonist. Displays neuroprotective efficacy in vitro.
Racemate also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Neuroprotection of S(+) KA isomer in global forebrain ischemia.
Proescholdt et al.
Brain Res., 2001;904:245
Low dose of S(+)-KA prevents long-term potentiation in pain pathways under strong opioid analgesia in the rat spinal cord in vivo.
Benrath et al.
Comparative pharmacology of the optical isomers of KA in mice.
Ryder et al.
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