Chemical Name: [4-(Tetradecanoylamino)benzyl]phosphonic acid disodium salt
Biological Activity Inhibitor of autotaxin (IC50 = 9 nM). Displays similar inhibitory effects at all three autotaxin isoforms (α, β and γ). Exhibits no affinity for lysophosphatidic acid receptor 1 (LPA1) at concentrations up to 10 μM. Inhibits LPA release from adipocytes (IC50 = 90 nM).
Soluble to 100 mM in 1eq. NaOH
Store at -20°C
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