Endothelin receptor agonist (EC50
values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo
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Comparison of responses to sarafotoxins 6a and 6c in pulmonary and systemic vascular beds.
Minkes et al.
Differences between endothelial receptors mediating contraction of guinea-pig aorta and pig coronary artery.
Schoeffter and Randriantsoa
Endothelin-induced nociception in mice: mediation by ETA and ETB receptors.
Raffa et al.