STEARDA

Catalog # Availability Size / Price Qty
2204/10
Cat.No. 2204 - STEARDA | C26H45NO3 | CAS No. 105955-10-0
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Description: Endogenous lipid, active in vivo. Enhances effects of endovanilloids at TRPV1 receptors
Alternative Names: N-Stearoyldopamine

Chemical Name: N-[2-(3,4-Dihydroxyphenyl)ethyl]octadecanamide

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB1 receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC50 > 25 μM). However, potentiates TRPV1-mediated effects of NADA in vitro and in vivo; enhances effects on intracellular Ca2+ (EC50 lowered 3-fold) and nociception. Also inhibits arachidonate 5-lipoxygenase (IC50 = 16 nM).

Technical Data

M.Wt:
419.64
Formula:
C26H45NO3
Solubility:
Soluble to 5 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
105955-10-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for STEARDA

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