Induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction at 1 μ
M. Inhibits cardiomyocyte differentiation at 5 μ
M. Potently inhibits CK1ε
, and CK1δ
values are 6.4, 6.7 and 6.8 nM respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold under agreement from ETPL and its Affiliates including Bioprocessing Technology Institute.
Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling.
Laco et al.