Catalog Number: 5384
Chemical Name: 4-(2-(2-Fluorophenyl)-4-(fluorophenyl)-1H-imidazol-5-yl)pyridine
Biological Activity
Induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction. Potently inhibits p38α, CK1δ and CK1ε (IC50 values are 20, 32 and 32 nM respectively).
Technical Data
  • M.Wt:
    333.33
  • Formula:
    C20H13F2N3
  • Solubility:
    Soluble to 100 mM in DMSO and to 20 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under agreement from the Agency for Science, Technology and Research (A*STAR), ETPL, and affiliates including the Bioprocessing Technology Institute.
Background References
  1. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling.
    Laco et al.
    J.Mol.Cell.Cardiol, 2014;

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