Tau [p Ser324] Antibody (4E8) - BSA Free

Novus Biologicals | Catalog # NBP3-26409

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4E8 expressed in HEK293

Format

BSA Free
View all Tau Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human Tau [p Ser324] [UniProt P10636]

Modification

p Ser 324

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tau [p Ser324] Antibody (4E8) - BSA Free

Tau [p Ser324] Antibody (4E8)

Immunocytochemistry/Immunofluorescence: Tau [p Ser324] Antibody (4E8) [NBP3-26409] -

Immunocytochemistry/Immunofluorescence: Tau [p Ser324] Antibody (4E8) [NBP3-26409] - Staining of SH-SY5Y cells with Tau [p Ser324] Antibody (4E8) at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L).

Applications for Tau [p Ser324] Antibody (4E8) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:20-1:200

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, and 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Tau

Tau is a microtubule binding protein that promotes microtubule assembly and stability. Tau is found to be the major component of the paired helical filaments (PHFs) found in the brains of patients with Alzheimer disease (AD) (1,2). Tau is hyperphosphorylated in PHFs, and specific phosphorylation sites have been implicated in the loss of Tau's association with the membrane cortex during AD disease state, including Ser 199/202, Thr 231, and Ser 393/404 (3). Glycogen synthase kinase-3, or GSK-3, phosphorylates Tau on Ser 396 (4).

Long Name

Microtubule-Associated Protein Tau

Alternate Names

MAPT, MSTD, MTBT1, Neurofibrillary tangle protein, PPND

Gene Symbol

MAPT

Additional Tau Products

Product Documents for Tau [p Ser324] Antibody (4E8) - BSA Free

Certificate of Analysis

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Product Specific Notices for Tau [p Ser324] Antibody (4E8) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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