Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

TLR6 antibody was raised against a peptide corresponding to 13 amino acids near the center of human TLR6. The immunogen is located within amino acids 390 - 440 of TLR6.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit TLR6 Antibody - BSA Free (NBP1-76664) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for TLR6 Antibody - BSA Free

Western Blot: TLR6 AntibodyBSA Free [NBP1-76664]

Western Blot: TLR6 AntibodyBSA Free [NBP1-76664]

Western Blot: TLR6 Antibody [NBP1-76664] - Jurkat cell lysate with TLR6 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
TLR6 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: TLR6 Antibody - BSA Free [NBP1-76664] -

Immunocytochemistry/ Immunofluorescence: TLR6 Antibody - BSA Free [NBP1-76664] - Immunocytochemistry of TLR6 in Jurkat cells with TLR6 antibody at 2 ug/mL.

Applications for TLR6 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

0.5-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TLR6

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.

Long Name

Toll-like Receptor 6

Alternate Names

CD286

Gene Symbol

TLR6

Additional TLR6 Products

Product Documents for TLR6 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TLR6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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