Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50
= 0.4 μ
M), more active than the (+) enantiomer
(Cat. No. 0579). Selective over ErbB2.
Soluble to 30 mM in DMSO
Desiccate at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases.
Gazit et al.