Potent and selective inhibitor of MMP-3 (IC50
= 5.9 nM). Displays selectivity over a range of MMPs (IC50
values are 73, 840, 1790, 1900 and 51000 for MMP-13, MMP-9, MMP-2, MMP-14 and MMP-1 respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold for research purposes under agreement from Pfizer Inc.
Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (stromelysin-1).
Fray and Dickinson
The citations listed below are publications that use Tocris products. Selected citations for UK 356618 include:
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