VH 032 - linker 1

Catalog # Availability Size / Price Qty
6463/25
Cat.No. 6463 - VH 032 - linker 1 | C30H45N5O7S.HCl | CAS No. 2097971-11-2
1 Image
Description: VH 032-PEG3-amine

Chemical Name: (2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

Purity: ≥95%

Product Details
Reviews

Biological Activity

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Technical Data

M.Wt:
656.23
Formula:
C30H45N5O7S.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2097971-11-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. Selective small molecule induced degradation of the BET bromodomain protein BRD4.
    Zengerle et al.
    ACS.Chem.Biol., 2015;10:1770
  2. Waste disposal-An attractive strategy for cancer therapy.
    Salami et al.
    Science, 2017;355:1163

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for VH 032 - linker 1

There are currently no reviews for this product. Be the first to review VH 032 - linker 1 and earn rewards!

Have you used VH 032 - linker 1?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.