VH 032 - linker 2
Chemical Name: (2S,4R)-1-((S)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
Biological ActivityFunctionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Selective small molecule induced degradation of the BET bromodomain protein BRD4.
Zengerle et al.
ACS Chem.Biol., 2015;10:1770
Waste disposal-An attractive strategy for cancer therapy.
Salami et al.
Impact of target warhead and linkage vector on inducing protein degradation: comparison of bromodomain and extra-terminal (BET) degraders derived from triazolodiazepine (JQ1) and tetrahydroquinoline (I-BET726) BET inhibitor scaffolds.
Chan et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for VH 032 - linker 2
There are currently no reviews for this product. Be the first to review VH 032 - linker 2 and earn rewards!
Have you used VH 032 - linker 2?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image