W146

Catalog # Availability Size / Price Qty
3602/1
Cat.No. 3602 - W146 | C16H27N2O4P | CAS No. 909725-61-7
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Description: Potent and selective S1P1 receptor antagonist
Alternative Names: ML 056

Chemical Name: [(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid

Purity: ≥98%

Product Details
Citations (4)
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Reviews

Biological Activity

Potent sphingosine-1-phosphate receptor S1P1 selective antagonist (Ki = 18 nM); displays no effect at S1P2, S1P3 or S1P5. Enhances capillary leakage and restores lymphocyte egress in vivo.

Technical Data

M.Wt:
342.37
Formula:
C16H27N2O4P
Solubility:
Soluble to 20 mM in 3eq. NaOH
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
909725-61-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citations for W146

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