The first potent, non-peptide, competitive bradykinin B2
receptor antagonist. In organ bath studies, WIN 64338 inhibits [3
H]-bradykinin binding on guinea pig trachea with nanomolar affinity but is not active in the rabbit aorta (the classical bradykinin B1
Soluble to 75 mM in DMSO
Desiccate at +4°C
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All Tocris products are intended for laboratory research use only.
Action of bradykinin in the submucosal plexus of guinea pig small intestine.
Hu et al.
Effects of peptide and nonpeptide antagonists of bradykinin B2 receptors on the venoconstrictor action of bradykinin.
Marceau et al.
Effects of WIN 64338, a nonpeptide bradykinin B2 receptor antagonist, on guinea-pig trachea.
Scherrer et al.
The citations listed below are publications that use Tocris products. Selected citations for WIN 64338 hydrochloride include:
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