ZD 2079 (CAS 178600-17-4): R&D Systems
Catalog Number: 2154
Chemical Name: 4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethoxy]-benzeneacetic acid hydrochloride
Biological Activity
β3-adrenoceptor agonist. Relaxes rat mesenteric artery and isolated aorta in vitro. Inhibits ob gene expression and circulating leptin levels in lean mice in vivo.
Technical Data
  • M.Wt:
    351.83
  • Formula:
    C18H21NO4.HCl
  • Solubility:
    Soluble to 25 mM in water
  • Purity:
    >99%
  • Storage:
    Desiccate at +4°C
  • CAS No:
    178600-17-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.
Background References
  1. Role of endothelium/nitric oxide in atypical β-adrenoceptor-mediated relaxation in rat isolated aorta.
    Brawley et al.
    Eur.J.Pharmacol., 2000;398:285
  2. Atypical β-adrenoceptors, different from β3-adrenoceptors, relax the rat isolated mesenteric artery.
    Kozlowska et al.
    Br.J.Pharmacol., 2003;140:3
  3. Rapid inhibition of ob gene expression and circulating leptin levels in lean mice by the β3-adrenoceptor agonists BRL 35135A and ZD2079.
    Trayhurn et al.
    Biochem.Biophys.Res.Comm., 1996;228:605
Citations:

The citations listed below are publications that use Tocris products. Selected citations for ZD 2079 include:

1 Citations: Showing 1 - 1

  1. Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat.
    Authors: Suárez Et al.
    Dis Model Mech 2014;7:129

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