ZD 2079

Catalog # Availability Size / Price Qty
2154/10
2154/50
ZD 2079 | CAS No. 178600-17-4 | Adrenergic beta-3 Receptor Agonists
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Description: β3-adrenoceptor agonist

Chemical Name: 4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethoxy]-benzeneacetic acid hydrochloride

Purity: ≥99%

Product Details
Citations (1)
Supplemental Products
Reviews

Biological Activity

β3-adrenoceptor agonist. Relaxes rat mesenteric artery and isolated aorta in vitro. Inhibits ob gene expression and circulating leptin levels in lean mice in vivo.

Technical Data

M.Wt:
351.83
Formula:
C18H21NO4.HCl
Solubility:
Soluble to 25 mM in water
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
178600-17-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.

Background References

  1. Role of endothelium/nitric oxide in atypical β-adrenoceptor-mediated relaxation in rat isolated aorta.
    Brawley et al.
    Eur.J.Pharmacol., 2000;398:285
  2. Atypical β-adrenoceptors, different from β3-adrenoceptors, relax the rat isolated mesenteric artery.
    Kozlowska et al.
    Br.J.Pharmacol., 2003;140:3
  3. Rapid inhibition of ob gene expression and circulating leptin levels in lean mice by the β3-adrenoceptor agonists BRL 35135A and ZD2079.
    Trayhurn et al.
    Biochem.Biophys.Res.Comm., 1996;228:605

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Citation for ZD 2079

The citations listed below are publications that use Tocris products. Selected citations for ZD 2079 include:

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