GDNF Family & Receptors

Molecule Antibodies Proteins
Artemin Mouse AF1085 2 Mouse 1085-AR 1,8
GDNF Human AF-212-NA 4 Rat 512-GF 4,5
Neurturin       Mouse 477-MN 8
GFR alpha 1 Human AF715 3 Rat 560-GR 5
  Rat AF560 8,9      
GFR alpha 2 Human AF613 3      
  Mouse AF429 6,8      
GFR alpha 3 Human AF670 3      
  Mouse AF2645 2,8      
GFR alpha 4 Mouse AF1677 7      
RET Human AF1485 3 Mouse 482-RT 10
  Mouse AF482 7      
  1. Ceyhan, G. et al. (2006) The neurotrophic factor artemin promotes pancreatic cancer invasion. Ann. Surg. 244:274.

    Sample Type: MiaPaCa2, T3M4, Colo-357, and SU86.86 cells (human pancreatic cancer)
  2. Elitt, C. et al. (2006) Artemin overexpression in skin enhances expression of TRPV1 and TRPA1 in cutaneous sensory neurons and leads to behavioral sensitivity to heat and cold. J. Neurosci. 26:8578.

    Sample Type: Mouse skin, DRG, and spinal cord sections
  3. Hauck, S. et al. (2006) GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells. Mol. Cell. Biol. 26:2746.

    Sample Type: Porcine retina sections
  4. Hamra, F. et al. (2007) Identification of neuregulin as a factor required for formation of aligned spermatogonia. J. Biol. Chem. 282:721.

    Sample Type: Rat germ cells
  5. Kjær, S. et al. (2006) Self-association of the transmembrane domain of RET underlies oncogenic activation of MEN2A mutations. Oncogene 25:7086.

    Sample Type: MG87 cells (mouse fibroblast)
  6. Lindfors, P.H. et al. (2006) Deficient nonpeptidergic epidermis innervation and reduced inflammatory pain in glial cell line-derived neurotrophic factor family receptor a2 knock-out mice. J. Neurosci. 26:1953.

    Sample Type: Mouse lumbar spinal cord ganglia, paw skin, and footpad sections
  7. Lindfors, P.H. et al. (2006) Ablation of persephin receptor glial cell line-derived neurotrophic factor family receptor a4 impairs thyroid calcitonin production in young mice. Endocrinology 147:2237.

    Sample Type: Mouse thyroid
  8. Malin, S. et al. (2006) Glial cell line-derived neurotrophic factor family members sensitize nociceptors in vitro and produce thermal hyperalgesia in vivo. J. Neurosci. 26:8588.

    Sample Type: Mouse sensory neurons and DRG sections
  9. Pierchala, B. et al. (2006) Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation. J. Neurosci. 26:2777.

    Sample Type: Rat sympathetic neuron lysates
  10. Taketomi, T. et al. (2005) Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia. Nat. Neurosci. 8:855.

    Sample Type: Mouse esophagus and colon